Min structure and mutation of SARS-CoV-2 S protein and potential mechanism of S protein-induced disease
10.3969/j.issn.1000-484X.2024.04.031
- VernacularTitle:SARS-CoV-2 S蛋白主要结构与突变及S蛋白引起疾病的潜在机制
- Author:
Xingjian LIU
1
;
Ruigang ZHANG
Author Information
1. 广东医科大学基础医学院生理学教研室,湛江 524002
- Keywords:
SARS-CoV-2 S protein;
ACE2;
Airway inflammation
- From:
Chinese Journal of Immunology
2024;40(4):857-861
- CountryChina
- Language:Chinese
-
Abstract:
SARS-CoV-2 caused severe threat to people's health all over the world,and has attracted widespread attention from researchers.The spike protein of SARS-CoV-2 is a key structure mediating the binding of the virus to its host.Therefore,it is im-portant to elucidate the mechanism of spike protein-induced immune responses.We've reviewed the structure of spike protein from al-pha to omicron variant,as well as the potential mechanisms of spike-induced in multiple systems,so as to provide a reference for dis-ease prevention and treatment.
