The left M1 intermittent theta burst stimulation(iTBS)modulated the topological properties of the brain functional network in stroke patients
10.3969/j.issn.1001-1242.2024.09.003
- VernacularTitle:左侧M1区间歇短阵脉冲刺激对脑卒中患者脑功能网络拓扑属性的影响
- Author:
Qing YANG
1
;
Shuo XU
;
Mengye CHEN
Author Information
1. 复旦大学附属华山医院康复医学科,上海市,200040
- Keywords:
stroke;
intermittent theta burst stimulation;
brain connectome;
brain functional network;
resting-state brain functional connectivity
- From:
Chinese Journal of Rehabilitation Medicine
2024;39(9):1259-1268
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the overall modulatory effect of the intermittent theta burst stimulation(iTBS),a novel non-invasive brain stimulation technique,on the topology of the brain functional network in stroke patients. Method:Sixteen patients with stroke were recruited.Based on their brain resting-state functional magnetic reso-nance images,the changes of the brain network topological properties,including the clustering coefficient,characteristic path length,local and global efficiency,"small-world",assortativity and hierarchy,were ana-lyzed before and after one session of left M1 iTBS. Result:The clustering coefficient,local efficiency and normalized hierarchy coefficient decreased significantly after one session of the iTBS,the global efficiency decreased near significantly,and the σ value of"small-world"increased close to significantly;while the other topological properties showed no significant change fol-lowing the iTBS intervention. Conclusion:The findings of the present study indicated that the left M1 iTBS may modulate the global net-work topological characteristics of the brain functional network in patients with stroke.
