Risk factors analysis of recurrent drug-eluting stent in-stent restenosis
10.3969/j.issn.1004-8812.2024.09.002
- VernacularTitle:复发性药物洗脱支架内再狭窄的危险因素分析
- Author:
Huan-Huan FENG
1
;
Xiao-Hang YUAN
;
Xin HU
;
Yan HAN
;
Xi ZHANG
;
Hao-Yi YE
;
Lei GAO
Author Information
1. 中国人民解放军总医院第一医学中心急诊科,北京 100853;中国人民解放军医学院,北京 100853
- Keywords:
Percutaneous coronary intervention;
Drug-eluting stent;
In-stent restenosis;
Recurrent in-stent restenosis
- From:
Chinese Journal of Interventional Cardiology
2024;32(9):489-495
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the predictors of recurrent in-stent restenosis(R-ISR)occurrence in drug-eluting stents(DES).Methods A total of 201 patients with ISR who received percutaneous coronary intervention(PCI)surgery in the First Medical Center of the Chinese PLA General Hospital from January 2010 to August 2023 were selected as the study objects,and the patients were divided into R-ISR group and non-R-ISR group according to their post-discharge angiography review.The clinical baseline data and the features of interventional surgery during the first ISR-PCI were retrospectively analyzed.Results Among the 201 patients,168 were males and 33 were females,with an average age of(61.97±10.02)years.The median interval between initial and follow-up angiography was 1.5 years.Patients were divided into two groups based on their radiographic reviews:R-ISR group(98 patients and 104 ISR lesions)and non-R-ISR group(103 patients and 111 ISR lesions).Multivariate Logistic regression analysis showed that the incidence of R-ISR was correlated with Ostial disease(OR 2.987,95％CI 1.343-6.642,P=0.007),plain old balloon angioplasty(POBA)performed for ISR lesions(OR 3.081,95％CI 1.293-7.343,P=0.011)and the maximum diameter stenosis rate of ISR lesions before surgery(OR 1.016,95％CI 1.002-1.030,P=0.022).Conclusions In patients currently receiving interventional therapy for ISR,Ostial disease,POBA treatment for ISR disease,and maximum diameter stenosis rate of ISR disease were associated predictors of R-ISR development.
