Results of one-year blood pressure follow-up after proximal and total renal artery denervation
10.3969/j.issn.1004-8812.2024.06.002
- VernacularTitle:肾动脉近段与全节段经皮去肾神经术1年血压随访结果
- Author:
Yi-Wen REN
1
;
Hao ZHOU
;
Wei-Jie CHEN
;
Hua-An DU
;
Bo ZHANG
;
Dan LI
;
Ming-Yang XIAO
;
Zi-Hao WANG
;
Zhi-Yu LING
;
Yue-Hui YIN
Author Information
1. 重庆医科大学附属第二医院心血管内科,重庆 400072;重庆医科大学附属第二医院心血管疾病神经调控研究治疗中心,重庆 400072
- Keywords:
Renal denervation;
Hypertension;
Full-length renal artery denervation;
Proximal renal artery denervation
- From:
Chinese Journal of Interventional Cardiology
2024;32(6):305-310
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the efficacy of renal proximal renal artery denervation(pRDN)and full-length renal artery denervation(fRDN)for treatment of hypertension.Methods Fifty-six hypertensive patients were enrolled and randomly assigned to full-length renal artery denervation group(n=25)and proximal renal artery denervation group(n=31).After the procedure,24-hour ambulatory blood pressure monitoring(24 h-ABPM)at 6 months and office blood pressure at 12 months was recorded for statistical analysis.Results The blood pressure at follow-up reduced significantly in both groups,while there was no significant difference between groups.The baseline office blood pressure in fRDN group and pRDN group was(180±15)/(104±10)mmHg and(180±12)/(103±8)mmHg,respectively,which decreased to(142±9)/(82±7)mmHg and(143±10)/(83±6)mmHg at 12 months postoperatively(P＜0.001 within groups and P＞0.05 between groups).The baseline 24 h-ABPM in the two groups was(162±13)/(95±8)mmHg and(160±12)/(94±8)mmHg,respectively,which decreased to(142±11)/(83±7)mmHg and(141±8)/(81±7)mmHg at 6 months postoperatively(P＜0.001 within groups and P＞0.05 between groups).However,there was no significant difference in the reduction of office blood pressure and ambulatory blood pressure between the two groups.No treatment-related adverse events were observed.Conclusions pRDN has similar antihypertensive effect to fRDN.
