Meta-analysis on the incidence of long COVID in Omicron-infected pa-tients
10.12138/j.issn.1671-9638.20246460
- VernacularTitle:奥密克戎毒株感染患者长新冠发病率的Meta分析
- Author:
Li-Yu WANG
1
;
Shi-Wei WU
;
Meng-Qi XU
;
Bao-Guang LIU
;
Lan-Ying PEI
;
Guo-Li YAN
;
Guan-Min ZHENG
Author Information
1. 河南中医药大学医学院,河南郑州 450046
- Keywords:
Omicron;
long COVID;
Meta-analysis;
SARS-CoV-2 infection;
COVID-19
- From:
Chinese Journal of Infection Control
2024;23(11):1384-1390
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the incidence of long CO VID symptoms in patients infected with Omicron variant of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2).Methods According to the inclusion and exclu-sion criteria of literatures,relevant studies without language restrictions published up to 2024 were retrieved from both Chinese and English databases.The Chinese databases were China National Knowledge Infrastructure(CNKI),Wanfang Database,and VIP databases,and the foreign databases were PubMed,Embase,and Web of Science.Three-step screening was used to select literatures,and Stata 17.0 software was used for analysis.Results The incidence of at least one sequelae in patients infected with Omicron variant was 29.62％.The most common symptoms included fatigue(19.10％),joint or muscle pain(11.06％),memory loss(9.71％),brain fog(8.80％),cough(8.42％),headache(7.26％),and sore throat(6.68％).Subgroup analysis results showed that with the extension of follow-up(3 months vs 6 months),the incidence of smell or taste changes was significantly re-duced(7.22％vs 0.78％).The higher the proportion of women(＜50％vs 50％-65％vs＞65％),the higher the incidence of joint or muscle pain(1.09％vs 4.62％vs 19.53％);the greater the median age(≥45 years vs＜45 years),the higher the incidence of chest pain or chest distress(0.90％vs 3.86％),all with statistically significant differences(all P＜0.05).Conclusion Incidence of long COVID in Omicron-infected patients is high and can cause various symptoms.Follow-up time,median age and gender proportion have significant impacts on the incidence of some symptoms.
