Antimicrobial resistance of Enterococcus spp.:surveillance report from Hunan Province Antimicrobial Resistance Surveillance System,2012-2021
10.12138/j.issn.1671-9638.20245432
- VernacularTitle:湖南省细菌耐药监测网2012-2021年肠球菌属细菌耐药性监测报告
- Author:
Chen-Chao FU
1
;
Li-Hua CHEN
;
Chen LI
;
Yan-Ming LI
;
Jun LIU
;
Xing-Wang NING
;
Guo-Min SHI
;
Jing-Min WU
;
Huai-De YANG
;
Hong-Xia YUAN
;
Ming ZHENG
;
An-Hua WU
;
Xun HUANG
;
Nan REN
Author Information
1. 中南大学湘雅医院医院感染控制中心,湖南长沙 410008;湖南省细菌耐药监测网办公室,湖南长沙 410008
- Keywords:
Enterococcus spp.;
bacterial resistance surveillance;
change in antimicrobial resistance;
antimicrobial agent;
Hunan Provincial Antimicrobial Resistance Surveillance System
- From:
Chinese Journal of Infection Control
2024;23(8):954-962
- CountryChina
- Language:Chinese
-
Abstract:
Objective To understand the antimicrobial resistance of clinically isolated Enterococcus spp.in Hunan Province.Methods Surveillance data of Enterococcus spp.resistance from member units of Hunan Provincial Anti-microbial Resistance Surveillance System from 2012 to 2021 were collected.Data were cleaned according to a unified method,and WHONET 5.6 software was adopted for statistical analysis.Results From 2012 to 2021,a total of 110 652 non-repetitive Enterococcus spp.strains were included in the analysis,mainly Enterococcus faecalis and Enterococcus faecium,accounting for 46.9％(n=37 774)and 45.9％(n=36 968),respectively,followed by En-terococcus avium(2.5％,n=1 982),Enterococcus gallinarum(1.8％,n=1 428),and Enterococcus casseliflavus(1.5％,n=1 185).The main specimen sources of Enterococcus spp.was urine(51.8％,n=57 350),followed by secretions(9.6％,n=10 660)and bile(8.5％,n=9 377).From 2012 to 2021,the resistance rates of Enteroco-ccus faecalis to ampicillin,teicoplanin,and vancomycin were 5.5％-12.0％,1.3％-2.0％,and 0.6％-1.4％,respectively.The resistance rates of Enterococcus faecium to ampicillin,teicoplanin,and vancomycin were 69.2％-85.0％,1.5％-2.8％,and 0.7％-2.5％,respectively.Except for linezolid and minocycline,the resistance rates of Enterococcus faecium to tested antimicrobial agents were all higher than those of Enterococcus faecalis.The re-sistance rates of Enterococcus faecalis and Enterococcus faecium to vancomycin decreased from 1.4％and 2.1％in 2012 to 0.6％and 0.7％in 2021,respectively,presenting a decreased trend.Conclusion Clinically isolated En-terococcus spp.maintain high antimicrobial susceptibility to vancomycin and teicoplanin.Resistance rates of Entero-coccus faecalis and Enterococcus faecium to vancomycin present decreased trends.
