Advances in the role of miRNA in atherosclerosis associated with obstructive sleep apnea
10.20039/j.cnki.1007-3949.2024.04.012
- VernacularTitle:miRNA在阻塞性睡眠呼吸暂停相关动脉粥样硬化中的作用研究进展
- Author:
Sha ZHANG
1
;
Weiying LIU
;
Juan WANG
;
Wenli FU
;
Leping LI
Author Information
1. 兰州大学第一临床医学院
- Keywords:
miRNA;
obstructive sleep apnea;
atherosclerosis
- From:
Chinese Journal of Arteriosclerosis
2024;32(4):364-368
- CountryChina
- Language:Chinese
-
Abstract:
Obstructive sleep apnea(OSA)is an independent risk factor for several cardiovascular diseases,and its characteristic intermittent hypoxic environment induces dysregulation of miRNA in cells and circulation,which promotes cellular dysfunction and metabolic disorders,and participates in the formation of atherosclerosis(As).This article re-views the potential role of miRNA in the occurrence and progression of OSA-related As,which helps to understand the mo-lecular pathways underlying the pathogenesis of OSA-related As and provides new insights for the development of miRNA based therapies for OSA-related cardiovascular diseases.
