Clinical characteristics of Ureaplasma urealyticum infection and colonization in extremely preterm infants
10.7499/j.issn.1008-8830.2403002
- VernacularTitle:超早产儿解脲脲原体感染及定植状态的临床特征分析
- Author:
Yan-Qiong WANG
1
;
Ya-Li ZENG
;
Xue-Yu CHEN
;
Zhi-Feng HUANG
;
Chuan-Zhong YANG
Author Information
1. 南方医科大学第一临床医学院深圳市妇幼保健院新生儿科,广东深圳 518000
- Keywords:
Ureaplasma urealyticum;
Infection;
Colonization;
Clinical charateristic;
Extremely preterm infant
- From:
Chinese Journal of Contemporary Pediatrics
2024;26(8):811-816
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical characteristics of Ureaplasma urealyticum(UU)infection and colonization in extremely preterm infants and its impact on the incidence of bronchopulmonary dysplasia(BPD).Methods A retrospective analysis was conducted on 258 extremely preterm infants who were admitted to the Department of Neonatology,Shenzhen Maternity and Child Healthcare Hospital,from September 2018 to September 2022.According to the results of UU nucleic acid testing and the evaluation criteria for UU infection and colonization,the subjects were divided into three groups:UU-negative group(155 infants),UU infection group(70 infants),and UU colonization group(33 infants).The three groups were compared in terms of general information and primary and secondary clinical outcomes.Results Compared with the UU-negative group,the UU infection group had significant increases in the incidence rate of BPD,total oxygen supply time,and the length of hospital stay(P<0.05),while there were no significant differences in the incidence rates of BPD and moderate/severe BPD between the UU colonization group and the UU-negative group(P>0.05).Conclusions The impact of UU on the incidence of BPD in extremely preterm infants is associated with the pathogenic state of UU(i.e.,infection or colonization),and there are significant increases in the incidence rate of BPD,total oxygen supply time,and the length of hospital stay in extremely preterm infants with UU infection.UU colonization is not associated with the incidence of BPD and moderate/severe BPD in extremely preterm infants.
