Clinical characteristics of children on prolonged mechanical ventilation due to different primary diseases
10.7499/j.issn.1008-8830.2311035
- VernacularTitle:不同原发病导致长期机械通气患儿的临床特征分析
- Author:
Jun-Zhen ZHU
1
;
Zheng LI
;
Li-Dan CUI
;
Shi-Yue MEI
;
Xiao-Lei LI
;
Bing FANG
;
Su-Yun QIAN
;
Yi-Bing CHENG
Author Information
1. 郑州大学附属儿童医院重症医学科,河南郑州 450018
- Keywords:
Prolonged mechanical ventilation;
Etiology;
Critical illness;
Child
- From:
Chinese Journal of Contemporary Pediatrics
2024;26(5):481-485
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the differences in clinical characteristics among children on prolonged mechanical ventilation(PMV)due to different primary diseases.Methods A retrospective analysis was performed on the clinical data of 59 pediatric patients requiring PMV from July 2017 to September 2022.According to the primary disease,they were divided into respiratory disease(RD)group,central nervous system(CNS)group,neuromuscular disease(NMD)group,and other disease group.The four groups were compared in terms of general information,treatment,and outcome.Results There were significant differences among the four groups in age,body weight,Pediatric Logistic Organ Dysfunction-2(PELOD-2)score,Pediatric Risk of Mortality Ⅲ(PRISM Ⅲ)score,analgesic and sedative treatment,nutrition supply,rehabilitation treatment,tracheotomy,successful ventilator weaning,and outcomes(P＜0.05).Compared with the RD group,the CNS group and the other disease group had a significantly higher age and a significantly higher proportion of children receiving rehabilitation treatment,and the CNS group had a significantly higher proportion of children receiving tracheotomy(P＜0.008).Compared with the other disease group,the CNS group and the NMD group had significantly lower PELOD-2 and PRISM Ⅲ scores,and the CNS group had a significantly higher proportion of children with successful ventilator weaning and a significantly higher proportion of children who were improved and discharged(P＜0.008).Conclusions There are differences in clinical characteristics among children receiving PMV due to different etiologies.Most children in the RD group have a younger age,and children in the CNS group have a relatively good prognosis.
