Recent research on the role of oxidative stress in the pathogenesis of attention deficit hyperactivity disorder
10.7499/j.issn.1008-8830.2309039
- VernacularTitle:氧化应激在注意缺陷多动障碍发病机制中的研究进展
- Author:
Chen-Lei WU
1
;
Meng-Fei WANG
;
Rong-Yi ZHOU
Author Information
1. 河南中医药大学第一附属医院儿科医院,河南郑州 450000;河南中医药大学儿科医学院,河南郑州 450000
- Keywords:
Attention deficit hyperactivity disorder;
Oxidative stress;
Neurotransmitter;
Neuroinflammation;
Cell apoptosis
- From:
Chinese Journal of Contemporary Pediatrics
2024;26(2):201-206
- CountryChina
- Language:Chinese
-
Abstract:
Attention deficit hyperactivity disorder(ADHD)is a common neurodevelopmental disorder in children and adolescents,and its etiology and pathogenesis are still unclear.Brain is the organ with the largest oxygen consumption in human body and is easily affected by oxidative imbalance.Oxidative stress has become the key research direction for the pathogenesis of ADHD,but there is still a lack of relevant studies in China.Based on the latest research findings in China and overseas,this article reviews the clinical and experimental studies on oxidative stress in ADHD and explores the association of oxidative stress with neurotransmitter imbalance,neuroinflammation,and cell apoptosis in the pathogenesis of ADHD,so as to provide new research ideas for exploring the pathogenesis of ADHD.[Chinese Journal of Contemporary Pediatrics,2024,26(2):201-206]
