A Meta-analysis of risk factors for delirium after brain tumor surgery
10.3760/cma.j.cn115682-20210707-03005
- VernacularTitle:脑肿瘤患者术后谵妄危险因素的荟萃分析
- Author:
Xuemei LI
1
;
Xiaofei YE
;
Weiying ZHANG
Author Information
1. 同济大学医学院，上海 200092
- Keywords:
Meta-analysis;
Neurosurgical procedure;
Brain neoplasm;
Postoperative delirium;
Risk factor
- From:
Chinese Journal of Modern Nursing
2022;28(5):611-617
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the risk factors for delirium after brain tumor surgery using a Meta-analysis, so as to provide a basis for clinical nurses to identify high-risk factors.Methods:Using the key words of delirium, brain tumor, surgery, risk factors and so on, the articles on delirium after brain tumor surgery were retrieved from authoritative databases at home and abroad such as PubMed, Web of Science, China National Knowledge Infrastructure (CNKI) and WanFang Data from January 1, 2001 to December 16, 2020. The quality of the article was evaluated and Meta-analysis was performed using Stata 16.0.Results:A total of 9 articles were included, and 13 risk factors were associated with delirium after brain tumor surgery. After Meta-analysis, age ≥50 years or ≤5 years [ OR=1.23, 95% CI (1.09-1.38) , P=0.001], history of alcoholism [ OR=2.12, 95% CI (1.09-4.13) , P=0.027] ], left and right bilateral brain tumors [ OR=2.19, 95% CI (1.30-3.69) , P=0.003], using benzodiazepines [ OR=4.11, 95% CI (2.03-8.30) , P<0.001], transfrontal craniotomy [ OR=3.12, 95% CI (1.94-5.00) , P<0.001], tracheal intubation [ OR=4.45, 95% CI (2.44-8.11) , P<0.001], physical restraint [ OR=2.86, 95% CI (1.82-4.51) , P<0.001] were risk factors for delirium after brain tumor surgery. Conclusions:Available evidence suggests that age ≥50 years or ≤5 years, history of alcoholism, left and right bilateral brain tumors, using benzodiazepines, transfrontal craniotomy, tracheal intubation, and physical restraint are risk factors for postoperative delirium in patients with brain tumors. High-risk patients should be identified, and preventive strategies should be adopted based on risk factors to reduce the incidence of postoperative delirium in this population.
