Guillain-Barré syndrome with a sensory level and positive anti-GM4-IgM antibody
10.19845/j.cnki.zfysjjbzz.2024.0178
- VernacularTitle:伴有感觉平面的抗GM4-IgM抗体阳性吉兰-巴雷综合征1例报告
- Author:
Yan LI
1
;
Dandan SHANG
;
Xuping ZHANG
Author Information
1. 郑州大学附属洛阳中心医院神经内科,河南 洛阳 471000;洛阳市脑血管(脑卒中)疾病临床医学研究中心,河南 洛阳 471000
- Keywords:
Sensory level;
GM4 antibody;
Guillain-Barré syndrome
- From:
Journal of Apoplexy and Nervous Diseases
2024;41(10):938-940
- CountryChina
- Language:Chinese
-
Abstract:
Guillain-Barré syndrome(GBS)is an immune-mediated acute inflammatory peripheral neuropathy.It primarily manifests as acute,symmetrical,flaccid paralysis of multiple nerve roots and peripheral neuropathy,with or without cranial nerve involvement.The two most common subtypes of GBS are acute inflammatory demyelinating polyneu-ropathy(AIDP)and acute motor axonal neuropathy(AMAN).Other less common types include acute motor sensory axo-nal neuropathy(AMSAN)and Miller-Fisher syndrome(MFS).In addition,other variants,such as pharyngeal-cervical-brachial variant,multiple cranial neuropathy,and paraplegia,have been increasingly reported.Therefore,GBS is gradu-ally being recognized as a spectrum of diseases.Previous studies have found and confirmed that ganglioside antibodies are associated with GBS,including anti-GM1,anti-GM2,anti-GM3,anti-GM4,anti-GD1a,anti-GD1b,anti-GT1a,anti-GT1b,and anti-GQ1b antibodies.However,GBS with a sensory level has been rarely reported.This report presents a case of anti-GM4 IgM-positive GBS with a sensory level following gastrointestinal surgery,which has not been previously reported.The findings of this study may help enhance awareness of this disease and reduce misdiagnosis.
