Application of wearable devices in assessing the short-term effect of subthalamic nucleus deep brain stimulation on gait in patients with Parkinson disease
10.19845/j.cnki.zfysjjbzz.2024.0088
- VernacularTitle:可穿戴设备评估帕金森病患者丘脑底核脑深部电刺激术后短期步态变化
- Author:
Jing HE
1
;
Wei DU
;
Zhuang CUI
Author Information
1. 北京医院神经内科,国家老年医学中心,中国医学科学院老年医学研究院,北京 100730
- Keywords:
Wearable devices;
Parkinson disease;
Deep brain stimulation;
Gait
- From:
Journal of Apoplexy and Nervous Diseases
2024;41(5):459-463
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the short-term effect of subthalamic nucleus deep brain stimulation(STN-DBS)on gait in patients with Parkinson disease(PD)using wearable devices.Methods Patients were required to wear wear-able sensors to perform timed up and go test(TUG)in the three different states of medication-off/stimulation-off,medication-on/stimulation-off,medication-off/stimulation-on,and spatiotemporal motion parameters were collected and analyzed.Results A total of 13 PD patients with a mean disease course of(8.00±1.38)years who underwent bilateral STN-DBS were included.Compared with the medication-off/stimulation-off state,STN-DBS shortened the total duration of TUG from(30.63±17.58)seconds to(19.50±5.78)seconds(P=0.003),increased step length from(39.44±14.34)cm to(49.46±13.41)cm(P=0.004),increased step speed from(0.68±0.27)m/s to(0.91±0.25)m/s(P=0.005),reduced the maximum trunk anteversion angle from(-25.32°±10.83°)to(-17.32°±12.49°)(P=0.047),and reduced the maximum trunk retroversion angle from(-22.03°±11.24°)to(-13.16°±12.83°)(P=0.022),all of which were statistically significant.Conclusion Within the short term after surgery,STN-DBS can shorten the total duration of TUG test,increase step length and speed,and reduce trunk anteversion angle during walking.
