Comparative study of different optimization methods in craniospinal irradiation
10.19745/j.1003-8868.2024175
- VernacularTitle:全脑全脊髓放疗中不同优化方法的对比研究
- Author:
Li-Li LIU
1
;
Shan XU
;
Fu-Rong RAN
;
Qiang LIU
Author Information
1. 重庆大学附属三峡医院肿瘤中心,重庆 404100
- Keywords:
craniospinal irradiation;
gradient optimization;
dynamic multi-leaf collimator automatic optimization;
volumetric modulated arc therapy
- From:
Chinese Medical Equipment Journal
2024;45(9):62-66
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the differences in dosimetric parameters between gradient optimization(GO)method and dynamic multi leaf collimator automatic optimization(dMLC-AO)method in craniospinal irradiation(CSI)to provide references for enhancing the feasibility of CSI planning of Monaco treatment planning system.Methods Fifteen patients undergoing CSI at some hospital were retrospectively selected,and a GO plan(enrolled into a GO group)and a dMLC-AO plan(enrolled into a dMLC-AO group)were designed for volumetric modulated arc therapy for each patient by the Monaco treatment planning system.The two groups were compared in terms of the dosimetric parameters of the planning target volume,dose transition zone and organ at risk.SPSS 24.0 statistical software was used for data analysis.Results The dMLC-AO group behaved slightly better than the GO group in D98％ and homogeneity index,with the differences being significant(P＜0.05),while the two groups were not different statistically in D2％,D50％and conformity index(P＞0.05).There were no significant differences between the two groups in radiation doses to the organs at risk except intestinal Dmean(P＞0.05).The GO group gained advantages over the dMLC-AO group in dose distribution conformity at the drop zone,and the target volume length covered by the 36 Gy isodose line for the intermdediate-section plan of the GO group was significantly longer than that of the dMLC-AO group.Conclusion GO method behaves better than dMLC-AO method in controlling effectively the dose drop at the dose transition zone of CSI plan.[Chinese Medical Equipment Journal,2024,45(9):62-66]
