Effect of orthokeratology combined with repeated low-level red-light therapy on progressive myopia in adolescents
10.13389/j.cnki.rao.2024.0120
- VernacularTitle:角膜塑形镜与RLRL联合应用在青少年进展性近视中的治疗效果
- Author:
Ying LIU
1
;
Lili XIE
;
Yanfang GUO
;
Tong AN
;
Dan YIN
;
Yong LI
;
Dongmei LIANG
Author Information
1. 053000 河北省衡水市,衡水市人民医院眼科
- Keywords:
orthokeratology;
repeated low-level red-light therapy;
progressive myopia;
adolescents;
myopia preven-tion and control
- From:
Recent Advances in Ophthalmology
2024;44(8):627-631
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of orthokeratology combined with repeated low-level red-light(RL-RL)therapy on progressive myopia in adolescents.Methods A total of 106 adolescents(212 eyes)with progressive my-opia admitted to our hospital from March 2020 to September 2022 were selected and randomly classified into an observation group(n=57,114 eyes)and a control group(n=49,98 eyes).Patients in the observation group received orthokeratology and RLRL therapy,and patients in the control group received orthokeratology only.All patients were followed up for 1 year.The uncorrected visual acuity(UCVA),axial length(AL),diopter,tear film lipid layer thickness(LLT),break-up time(BUT),subfoveal choroidal thickness(SFChT),and the incidence of complications at different time points were compared between the two groups.Results Analysis of variance on the UCVA,diopter,LLT,BUT and SFChT at differ-ent time points before and after treatment revealed a significant time effect and time × group interaction effect(all P＜0.05),but no statistical group effect(all P＞0.05).For the AL,there was a significant time effect(P＜0.05),but no time x group interaction effect or group effect(all P＞0.05).Twelve months after treatment,the UCVA,LLT decrease and SFChT thickening were greater in the observation group compared to the control group,while the diopter progression and AL increase were milder in the observation group than in the control group(all P＜0.05).Changes in BUT yielded no sta-tistical difference between the two groups(P＞0.05).The complication rate demonstrated no statistical difference between the two groups(P＞0.05).Conclusion The application of RLRL therapy combined with orthokeratology for progressive myopia in adolescents can effectively improve the UCVA and control the growth of AL and diopter,with high safety.
