Analysis of risk factors for decreased medication compliance of β receptor blocker in patients with coro-nary heart disease after PCI
10.3969/j.issn.1008-0074.2024.03.06
- VernacularTitle:冠心病患者PCI术后β受体阻滞剂用药依从性下降的危险因素分析
- Author:
Xiao-Xin HOU
1
;
Jun-Xia HAO
;
Xiao-Min ZHANG
Author Information
1. 河北北方学院附属第一医院心内科CCU,河北张家口 075000
- Keywords:
Coronary disease;
Angioplasty,balloon,coronary;
Adrenergic beta-antagonists;
Medication adher-ence;
Risk factors
- From:
Chinese Journal of cardiovascular Rehabilitation Medicine
2024;33(3):285-289
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the risk factors of decreased medication compliance of β-receptor blocker in patients with coronary heart disease(CHD)after percutaneous coronary intervention(PCI).Methods:A total of 160 CHD patients undergoing PCI from January 2020 to July 2021 in our hospital were selected.According to post-operative Morisky medication adherence scale(MMAS-8)score,they were divided into high compliance group(n=100,≥6 points)and low compliance group(n=60,＜6 points).Univariate and multivariate Logistic regression analysis were conducted to analyze the influencing factors of decreased medication compliance of β-receptor blocker in CHD patients after PCI.Results:The mean MMAS-8 score of 160 patients was(5.81±0.12)points.Com-pared with high compliance group,there were significant reductions in percentages of age＜60 years(74.00％vs.36.67％),high school or higher education(68.00％vs.40.00％),stent implanted duration＜2 years(54.00％vs.28.33％),family APGAR index score[(5.12±1.60)points vs.(4.52±2.10)points],proportion of APGAR score≥7 points(68.00％vs.33.33％),and significant rise in percentages of family income＜3000 RMB(34.00％vs.61.67％),self-paying(36.00％vs.60.00％),diabetes(47.00％vs.66.67％)and hypertension(42.00％vs.65.00％)in low compliance group,P＜0.05 or＜0.01.Multivariate Logistic regression analysis indicated that junior high school education,age ≥60 years,family income＜3000 RMB,self-paying,stent implanted duration≥2 years,hypertension and diabetes were independent risk factors for decreased medication compliance of β-re-ceptor blocker in CHD patients after PCI(OR=8.445～97725.056,P＜0.05 or＜0.01),while APGAR score ≥7 points was its independent protective factor(OR=0.005,P=0.001).Conclusion:The influencing factors for de-creased medication compliance of β-receptor blocker in CHD patients after PCI include age,stent implanted dura-tion,education level etc.It is necessary to focus on monitoring the medication of patients with risk factors and per-form intervention,which is helpful to improve medication compliance.
