Myasthenia gravis after allogeneic hematopoietic stem cell transplantation: Two case reports and literature review
10.3760/cma.j.cn121090-20240311-00089
- VernacularTitle:异基因造血干细胞移植后合并重症肌无力2例报告并文献复习
- Author:
Yajun SHI
1
;
Ying HAN
;
Xiaofei ZHANG
;
Rui XI
;
Hai BAI
;
Tao WU
Author Information
1. 中国人民解放军联勤保障部队第九四〇医院血液科，兰州 730050
- From:
Chinese Journal of Hematology
2024;45(10):956-959
- CountryChina
- Language:Chinese
-
Abstract:
The onset of myasthenia gravis (MG) after allogeneic hematopoietic stem cell transplantation (allo-HSCT) seriously threatens the survival of patients, since it is acute, and is prone to rapid progression. Two patients with acute myeloid leukemia (AML), who had undergone allo-HSCT developed shortness of breath, and gradually developed cervical weakness and dyspnea. The acetylcholine receptor (AChR) antibody and neostigmine test enabled the diagnosis of MG. The condition of the patients improved after treatment with pyridostigmine bromide, glucocorticoids and rituximab.
