Research progress on the early diagnosis of pediatric hemophagocytic lymphohistiocytosis
10.3760/cma.j.issn.1673-4912.2024.11.001
- VernacularTitle:儿童噬血细胞综合征早期诊断研究进展
- Author:
Xiulan LU
1
Author Information
1. 中南大学湘雅医学院附属儿童医院（湖南省儿童医院），长沙 410007
- Keywords:
Children;
Hemophagocytic lymphohistiocytosis;
Early diagnosis;
Predictive model;
Biomarker;
Diagnostic pathway
- From:
Chinese Pediatric Emergency Medicine
2024;31(11):801-805
- CountryChina
- Language:Chinese
-
Abstract:
Early diagnosis is crucial for improving the prognosis of hemophagocytic lymphohistiocytosis（HLH）.However，diagnosing HLH presents numerous challenges，including lack of specific clinical manifestations，difficulty in early recognition，complex diagnostic criteria，and lengthy testing periods for some diagnostic indicators.To address these clinical challenges，researchers both in China and abroad have conducted various studies aimed at developing new biomarkers，establishing methods for the early identification of suspected cases，optimizing predictive models and diagnostic criteria for different types of HLH，and creating clear clinical diagnostic pathways.This article summarized the research progress on the early diagnosis of pediatric HLH，providing a reference for advancing early diagnosis of the disease.
