Indications for therapeutic hypothermia and its applications on mild hypoxic-ischemic encephalopathy
10.3760/cma.j.issn.1673-4912.2024.10.005
- VernacularTitle:低温治疗指征与轻度缺氧缺血性脑病低温治疗现状
- Author:
Fan ZHANG
1
;
Laishuan WANG
Author Information
1. 复旦大学附属儿科医院新生儿诊疗中心 国家卫生健康委员会新生儿疾病重点实验室，上海 201102
- Keywords:
Neonate;
Therapeutic hypothermia;
Hypoxic-ischemic encephalopathy;
Treatment indication;
Adverse effects;
Multi-center randomized controlled trial
- From:
Chinese Pediatric Emergency Medicine
2024;31(10):746-750
- CountryChina
- Language:Chinese
-
Abstract:
Over the past two decades,therapeutic hypothermia has been the most important treatment for moderate to severe neonatal hypoxic-ischemic encephalopathy (HIE).However,due to the lack of uniformity in the grading assessment methods for HIE and the willingness of clinicians to actively treat,therapeutic hypothermia is now being increasingly implemented in infants with mild HIE.At the same time,owing to the insufficient knowledge regarding the effectiveness and safety of treatment beyond the established indications,concerns about this situation have been arisen.The ongoing large-scale multi-center randomized controlled trial may change this situation in the future.
