Research advances on the role of cell senescence in chronic wound healing
10.3760/cma.j.cn501225-20220928-00424
- VernacularTitle:细胞衰老在慢性创面愈合中的作用研究进展
- Author:
Shaoyihan FANG
1
;
Dewu LIU
Author Information
1. 南昌大学第一附属医院烧伤整形与创面修复医学中心，南昌 330006
- Keywords:
Cell aging;
Wound healing;
Chronic wounds;
Senescence-associated secretory phenotype
- From:
Chinese Journal of Burns
2023;39(8):795-800
- CountryChina
- Language:Chinese
-
Abstract:
Chronic wounds bring huge pressure and difficulties to patients, their families, and society due to their long-term refractory characteristics and serious poor prognosis. Recently, more and more evidences have proven that cell senescence exists in chronic wounds and affects wound healing. This article reviews the characteristics of cell senescence in chronic wounds, discusses the relationship between cell senescence and chronic wound healing, and summarizes current series of anti-senescence strategies to bring out the possibility of treating chronic wounds with cell senescence as a potential target.
