New progress on the clinical study of antiviral therapy for chronic hepatitis B in children
10.3760/cma.j.cn501113-20240408-00181
- VernacularTitle:儿童慢性乙型肝炎抗病毒治疗的临床研究新进展
- Author:
Peiyao FAN
1
;
Jing LI
;
Fusheng WANG
Author Information
1. 解放军总医院第五医学中心感染病医学部 国家感染性疾病临床研究中心，北京 100039
- Keywords:
Chronic hepatitis B;
Child;
Antiviral therapy;
Prognosis;
Clinical cure
- From:
Chinese Journal of Hepatology
2024;32(5):394-398
- CountryChina
- Language:Chinese
-
Abstract:
Diagnosis and treatment of hepatitis B virus (HBV) infection in children is a hotspot of concern in the field of HBV infection. This article reviews the current status and progress of antiviral treatment for children with chronic hepatitis B (CHB) in recent years, focusing on clinical issues such as the choice of antiviral treatment regimen for children with HBeAg-positive CHB (immune-clearance phase), the necessity of antiviral treatment for children with HBeAg-positive HBV infection (immune-tolerance phase), and the timing of antiviral treatment for infants with HBV infection, to explore the relevant factors that may affect the clinical cure of children with CHB. At the same time, based on the expert consensus on the prevention and treatment of children with CHB just published by Chinese experts, relevant diagnosis and treatment plans are proposed, with a view to providing reference and basis for clinical decision-making in children with CHB.
