Research progress of hepatic sinusoidal obstruction syndrome
10.3760/cma.j.cn501113-20221110-00556
- VernacularTitle:肝窦阻塞综合征研究进展
- Author:
Ziliang KE
1
;
Yulan LIU
Author Information
1. 北京大学人民医院消化科，北京 100044
- Keywords:
Hepatic sinusoidal obstruction syndrome;
Hepatic veno-occlusive disease;
Diagnosis;
Treatment;
Clinical prevention;
Progress
- From:
Chinese Journal of Hepatology
2022;30(12):1298-1303
- CountryChina
- Language:Chinese
-
Abstract:
Hepatic sinusoidal obstruction syndrome (HSOS) is a hepatic vascular disease that begins with injury to hepatic sinusoidal endothelial cells, and has a fatality rate of over 80% in its severe form. Therefore, early diagnosis and treatment are crucial to delay HSOS progression and reduce mortality. However, clinicians' understanding of the disease is still insufficient, and the clinical manifestations of the disease are similar to liver diseases caused by other etiologies, resulting in a high rate of misdiagnosis. This article mainly introduces the HSOS recent developments in the etiology and pathogenesis, clinical manifestations and auxiliary examinations, diagnostic criteria, treatment, and prevention.
