Advances in the role of mitochondrial respiratory chain enzyme complexes in myocardial ischemia-reperfusion injury
10.3969/j.issn.1006-5725.2024.15.022
- VernacularTitle:线粒体呼吸链酶复合物在心肌缺血再灌注损伤中的作用进展
- Author:
Zhu LI
1
;
Yan WANG
;
Wenjing ZHOU
;
Haiying WANG
Author Information
1. 遵义医科大学附属医院麻醉科(贵州遵义 563003)
- Keywords:
myocardial ischemia reperfusion injury;
mitochondrial enzyme complexes;
mitochondrial respiratory chain
- From:
The Journal of Practical Medicine
2024;40(15):2172-2176
- CountryChina
- Language:Chinese
-
Abstract:
Myocardial ischemia reperfusion injury(MIRI)is a common cardiovascular complications,which is a major problem for many clinical scholars.To improve the prognosis of MIRI,many scholars have devoted to the research of its mechanism,and founded that mitochondria are closely related to the occurrence of MIRI,where the function of mitochondrial respiratory chain enzyme complex is impaired,and energy metabolism disor-ders play a key role in the process of MIRI.The aim of this review is to describe the changes of mitochondrial respi-ratory chain enzyme complex in MIRI and its effect on MIRI,and to provide a basis for finding new and effective therapeutic targets for MIRI.
