Core decompression combined with BMP activity inducing rod implantation for early femoral head necrosis
10.3969/j.issn.1006-5725.2024.09.017
- VernacularTitle:髓芯减压联合骨形成蛋白活性诱导棒植入术治疗早期股骨头坏死的效果
- Author:
Liming ZHENG
1
;
Feng WEN
;
Wei WANG
;
Zhiwen ZHANG
Author Information
1. 湖北中医药大学针灸骨伤学院(武汉 430061)
- Keywords:
early osteonecrosis of the femoral head;
core decompression;
calcium phosphate cement;
recombinant human bone morphogenetic protein-2;
BMP activity induced rod
- From:
The Journal of Practical Medicine
2024;40(9):1280-1285
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of core decompression combined with bone-morphogenetic proteins(BMP)activity inducing rod implantation in the treatment of early-stage femoral head necrosis.Methods Retrospective analysis of 116 patients with early-stage femoral head necrosis from June 2018 to June 2022 were divided into core decompression combined with BMP activity inducing rod group(BMP group)and allograft bone group.Sixty cases in the BMP group were treated with core decompression combined with implantation of BMP-activated induced rods,and 56 cases in the allograft group were treated with core decompression combined with bone grafting of the allograft bone by punching and compression.The differences in hip Harris scores and visual analogue scores(VAS)of pain between the two groups at preoperative,6 months postoperative and 1 year postop-erative,and the patient treatment response and femoral head survival rate at 1 year postoperative were compared.Results All patients were followed-up,and the difference between the preoperative VAS score and Harris score of the two groups was not statistically significant(P＞0.05),and the VAS score and Harris score of the two groups were significantly improved at 6 months and 1 year after operation,and the BMP group was better than the allograft bone group,with significant difference(P＜0.05).At 1 year after surgery,the Harris hip score excellence rate of the BMP group was higher than that of the allograft bone group,and the difference was statistically significant(P＜0.05);the femoral head survival rate of the BMP group was higher than that of the allograft bone group,and the difference was statistically significant(P＜0.05).Conclusions Core decompression combined with BMP activity induced rod implantation was effective in the treatment of early femoral head necrosis,which accelerated the induction of new bone formation,improved the quality of new bone,provided biomechanical support for the femoral head,and effectively avoided femoral head collapse.Moreover,it has good biocompatibility and couldbe degraded and absorbed in the body,which is worthy of clinical promotion.
