Diagnosis and treatment strategies for end-stage liver disease combined with infection
10.3760/cma.j.cn501113-20200619-00334
- VernacularTitle:终末期肝病合并感染的诊疗策略
- Author:
Yuemin NAN
1
;
Lingdi LIU
Author Information
1. 河北医科大学第三医院 河北省慢性肝病肝纤维化机制研究重点实验室中西医结合肝病科，石家庄 050051
- Keywords:
End stage of liver disease;
Infection;
Multi-drug resistant bacteria;
Antibiotic therapy;
Supportive treatment
- From:
Chinese Journal of Hepatology
2020;28(7):545-547
- CountryChina
- Language:Chinese
-
Abstract:
Patients with end-stage liver disease are more likely to be infected due to the changes in the liver’s internal environment, low immune defense capabilities and reduced gut barrier function. Common infections include pneumonia, spontaneous bacterial peritonitis, biliary and urinary tract infections, skin and soft tissue infections, and spontaneous bacteremia, which in severe cases can lead to sepsis and septic shock. Importantly, infections can aggravate and progress to the liver and damage correlated organs, and thus can be life-threatening in severe cases. Therefore, early detection and diagnosis, as well as the use of effective antibacterial agents, and supportive treatment are keys to saving patients' lives.
