Effect of sublingual nitroglycerin on CT imaging of peripheral arteries of knee joint in patients with knee osteoarthritis
10.3969/j.issn.1002-1671.2024.10.022
- VernacularTitle:舌下含服硝酸甘油对膝骨性关节炎患者膝关节周围动脉CT成像的影响
- Author:
Qinxia SONG
1
;
Xiangfa WANG
;
Feng CHEN
Author Information
1. 安庆市立医院医学影像科,安徽 安庆 246003
- Keywords:
nitroglycerin;
dual-source computed tomography;
computed tomography angiography;
knee osteoarthritis
- From:
Journal of Practical Radiology
2024;40(10):1678-1682
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of sublingual nitroglycerin(NTG)tablets on the quality of computed tomography angiography(CTA)around the knee joint in patients with knee osteoarthritis(KOA).Methods A total of 100 patients with KOA were included in the study and randomly divided into two groups before lower limb CTA(40 cases in the medication group and 60 cases in the control group).The contrast-to-noise ratio(CNR)of CTA images were compared,and the overall image quality and vascular grading were evaluated and compared using the Likert 5-point method.The diameter of the popliteal artery(PA),anterior tibial artery(ATA),posterior tibial artery(PTA),peroneal artery(PeA),descending genicular artery(DGA),lateral superior genicular artery(LSGA),medial superior genicular artery(MSGA),middle genicular artery(MGA),medial inferior genicular artery(MIGA),lateral inferior genicular artery(LIGA),and anterior tibial recurrent artery(ATRA)were measured.Furthermore,the number of visible arteries around the knee joint between the two groups were calculated and compared.Results The CNR and overall CTA image quality of arteries around the knee joint in the medication group were significantly higher than those in the control group(P＜0.05).Moreover,the lumen diameter of the PA and its branches significantly increased in the medication group(P＜0.05).In comparison to control group,the number of visible vessels significantly increased in the medication group(P＜0.05).Conclusion Sublingual administration of NTG during CTA examination can effectively increase arterial diameter around the knee joint,resulting in improved image quality as well as an increased number of visible arteries.
