Molecular mechanism and pathological evaluation strategies for recurrence and metastasis of liver cancer
10.3760/cma.j.issn.1007-3418.2016.05.002
- VernacularTitle:肝癌复发转移的分子机制与病理学评估策略
- Author:
Wenming CONG
1
Author Information
1. 第二军医大学东方肝胆外科医院病理科
- Keywords:
Carcinoma,hepatocellular;
Neoplasm metastasis;
Pathology;
Diagnosis;
Recurrence;
Mechanism
- From:
Chinese Journal of Hepatology
2016;24(5):324-326
- CountryChina
- Language:Chinese
-
Abstract:
The strong invasiveness and metastasis of hepatocellular carcinoma (HCC) are not only the important pathological mechanisms of high recurrence rate and poor long-term outcome,but also the important pathological basis for developing individualized regimens to control metastasis and recurrence in clinical practice.This article introduces the important molecular events in invasion-metastasis cascade discovered in recent years,including the formation mechanism of metastatic niches,methods for molecular pathological evaluation,and standardized pathological diagnosis.