Comparative study on the application effect of three kinds of foam dressings in wound healing of mice with full-thickness defects
10.3760/cma.j.issn.1674-2907.2016.29.015
- VernacularTitle:三种泡沫敷料在小鼠全层缺损创面修复中的应用效果比较
- Author:
Jing PENG
1
;
Rui XU
;
Qiangfang YU
Author Information
1. 401147 重庆市精神卫生中心女病区
- Keywords:
Skin care;
Foam dressings;
Wound healing;
Granulation tissue
- From:
Chinese Journal of Modern Nursing
2016;22(29):4203-4205,4206
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the efficacy and feasibility of three kinds of foam dressings in the wound healing.Methods Totally 30 BALB/C mice were divided into three groups, and 1×1 cm full-thickness defects on the back of mice were prepared. The wounds were covered with Comfeel dressing, Mepilex dressing and Allevyn dressing, and then the wounds were sutured and fixed. Five mice were selected in each group randomly at day 3 and day 7 after surgery, then the results were analyzed with Image-pro plus 6. 0 software. Situation of epithelization and granulation tissue were analyzed by quantitative observation analysis from the perspective of pathology.Results Wound healing rate of Allevyn dressing group at day 3 and day 7 after surgery were 31.79% and 78.45%, which were higher than the data of the other two groups (P<0.05). Pathological analysis found that, in the Allevyn dressing group at 7 d after surgery, the length of new epithelium of the wound tissue was longer than the other two groups; at the same time, the wound granulation tissue of the Allevyn dressing group was thicker than that of the Mepilex dressing group.Conclusions Among the three kinds of foam dressings, Allevyn dressing can significantly promote the granulation tissue growth of wound and epithelization, and then promote the wound healing.
