IgA nephropathy with mesangial type Ⅲ collagen deposition:2 cases report
10.3969/j.issn.1672-8467.2024.03.019
- VernacularTitle:IgA肾病伴系膜区Ⅲ型胶原沉积2例
- Author:
Jie-Bo HUANG
1
;
Xiao-Fan CAI
;
Zhong-Hua ZHAO
;
Zhi-Gang ZHANG
;
Qiang SHEN
;
Hao WANG
;
Hui-Juan WU
Author Information
1. 上海中医药大学附属普陀医院肾内科 上海 200062
- Keywords:
glomerulonephritis;
IgA nephropathy;
type Ⅲ collagen(Col Ⅲ);
mesangial region
- From:
Fudan University Journal of Medical Sciences
2024;51(3):426-430
- CountryChina
- Language:Chinese
-
Abstract:
As interstitial collagen,type Ⅲ collagen(Col Ⅲ)does not express in normal glomeruli.However,in Col Ⅲ nephropathy,a large amount of Col Ⅲ deposit in the mesangial and subendothelial area of the glomeruli.IgA nephropathy with Col Ⅲ deposition was extremely rare.In this article,we reported two cases of such disease.After treating with immunosuppressive agents or traditional Chinese medicine decoction,the renal function of the two patients remained stable and the urinary protein levels reduced significantly.
