Gestational trophoblastic neoplasia with uterine arteriovenous malformation:vascular characteristics and clinical follow-up results
10.3969/j.issn.1672-8467.2024.03.004
- VernacularTitle:妊娠滋养细胞肿瘤合并子宫动静脉畸形与预后相关性分析
- Author:
Qing ZHOU
1
;
Yuan-Tao LIU
;
Feng-Hua MA
;
Xin LU
;
He ZHANG
;
Guo-Fu ZHANG
Author Information
1. 复旦大学附属妇产科医院放射科 上海 200011
- Keywords:
gestational trophoblastic neoplasia(GTN);
uterine arteriovenous malformation(UVAM);
contrast-enhanced magnetic resonance angiography(CE-MRA);
magnetic resonance imaging
- From:
Fudan University Journal of Medical Sciences
2024;51(3):315-322
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigated vascular characteristics and clinical follow-up results of gestational trophoblastic neoplasia(GTN)with uterine arteriovenous malformation(UAVM)using contrast-enhanced magnetic resonance angiography(CE-MRA).Methods Patients clinically suspected of GTN at Obstetrics and Gynecology Hospital,Fudan University from Dec 2015 to Dec 2020 were selected.Imaging characteristics of conventional magnetic resonance imaging and CE-MRA before treatment.The International Federation of Gynecology and Obstetrics(FIGO)2000 clinical staging and prognosis scoring system was used to evaluate the severity of the condition and related risk factors,the treatment methods(chemotherapy,surgical treatment,and arterial embolization)and prognosis determined during follow-up were recorded.Results A total of 44 cases were included,including 5 cases of placental site trophoblastic tumor(PSTT)and 39 cases of the other GTN.There were 3 cases of PSTT combined with UAVM and 23 cases of the other GTN combined with UAVM.Thirty-nine cases of the other GTN were divided into two groups according to the presence or absence of UAVM.Data regarding the β-human chorionic gonadotropin(β-hCG)value(＜10 000 mIU/mL and≥10 000 mIU/mL)were evaluated using Chi-square test,and the difference was statistically significant(P=0.001).The average FIGO scores of the two groups were 4.19±3.69 and 6.70±3.39,and the difference was statistically significant(P=0.035).Conclusion When β-hCG value≥10 000 mIU/mL,the probability of UAVM occurrence increases.The higher the prognosis score is,the more possibility of formation of UAVM.The use of CE-MRA technology helps to better diagnose UAVM.
