Common issues and solutions in intraoperative frozen pathological diagnosis of small pulmonary nodules
10.3760/cma.j.cn112151-20231218-00421
- VernacularTitle:肺部小结节术中冷冻切片病理诊断中的常见问题及解决策略
- Author:
Lei ZHU
1
;
Yuchen HAN
Author Information
1. 上海市胸科医院 上海交通大学医学院附属胸科医院病理科，上海 200030
- Keywords:
Lung neoplasms;
Frozen sections;
Diagnosis, differential
- From:
Chinese Journal of Pathology
2024;53(8):777-782
- CountryChina
- Language:Chinese
-
Abstract:
With the development of chest CT screening, surgically resected lung tumors have shifted from predominantly large masses to predominantly small nodules. The intraoperative frozen diagnosis of pulmonary small nodules faces many challenges, such as the accurate understanding about the concepts of adenocarcinoma in situ, minimally invasive adenocarcinoma and lepidic adenocarcinoma, as well as their differential diagnosis with small size invasive adenocarcinoma, benign tumors (such as bronchiolar adenoma, sclerosing pneumocytoma, etc.), metastatic tumors and so on. This study summarizes some common problems encountered in the intraoperative frozen diagnosis of small pulmonary nodules in daily practice, focusing on the diagnosis and differential diagnosis of adenocarcinoma, in order to make the accurate intraoperative frozen diagnosis of small pulmonary nodules and diminish misdiagnosis.
