Interpretation on genetic tumour syndromes in the 5th WHO classification of paediatric tumours: part Ⅱ
10.3760/cma.j.cn112151-20230926-00216
- VernacularTitle:第5版WHO儿童肿瘤分类遗传性肿瘤综合征解读（二）
- Author:
Yuan FANG
1
;
Lejian HE
;
Lian CHEN
Author Information
1. 复旦大学附属儿科医院安徽医院（安徽省儿童医院）病理科，合肥 230051
- Keywords:
World Health Organization;
Pediatrics;
Tumor;
Genetics;
Syndrome
- From:
Chinese Journal of Pathology
2024;53(3):224-229
- CountryChina
- Language:Chinese
-
Abstract:
WHO firstly published the classification of paediatric tumours, in which genetic tumour syndromes were introduced as a separate chapter, covering the clinicopathological features, molecular genetic alterations, and diagnostic criteria of various tumor susceptibility syndromes common in children. This article briefly introduces and interprets 5 hotspot genetic tumour syndromes (neurofibromatosis type 1, naevoid basal cell carcinoma syndrome, von Hippel-Lindau syndrome, familial adenomatous polyposis and xeroderma pigmentosum) based on relevant literature, in order to bring new perspectives and insights to pathologists and clinicians.
