Vaginal tubulo?squamous polyp: a clinicopathological analysis of four cases

VernacularTitle:阴道壁管状鳞状上皮息肉四例临床病理学分析
Author: Feng ZHOU ¹ ; Haiyan SHI ; Yun LIANG ; Xiaoduan CHEN
Author Information

1. 浙江大学医学院附属妇产科医院病理科
Keywords: Vaginal diseases; Polyps; Diagnosis,differential
From: Chinese Journal of Pathology 2019;48(6):462-465
CountryChina
Language:Chinese
Abstract: Objective To investigate clinicopathological characteristics of vaginal tubulo?squamous polyp (TSP). Methods Clinical and pathological data of 4 cases of vaginal TSP diagnosed at Women′s Hospital, School of Medicine, Zhejiang University from 2007 to 2018 were analyzed by hematoxylin?eosin and EnVision two?step immunohistochemical staining technique. Results The age of the 4 patients ranged from 62 to 71 years, with a mean of 66 years. Histologically, the polyps consisted of an admixture of squamous epithelium and tubules within a fibrous stroma. Immunohistochemically, the cells lining the tubules showed positive staining of prostatic acid phosphatase (PSAP) and/or prostate?specific antigen (PSA) in all 4 cases. Available follow?up in 3 patients for 4 to 6 months (mean of 5.3 months) showed no tumor recurrence. Conclusion TSP is an under?recognized benign vaginal polypoid disease that may develop from paraurethral Skene glands.