Electroencephalographic mechanisms of loss of consciousness induced by propofol
- VernacularTitle:丙泊酚诱导意识消失的脑电机制
- Author:
Fei TAO
1
;
Weidong GU
Author Information
- Keywords: Electroencephalography; Propofol; Loss of consciousness; Brain function
- From: The Journal of Clinical Anesthesiology 2024;40(5):532-535
- CountryChina
- Language:Chinese
- Abstract: Electroencephalography can continuously record the spontaneous and rhythmic electrical activity of local neurons in the brain region in real time and evaluate the functional state of the brain,which is a tool for monitoring brain activity.It has been widely used in the research fields of psychology,cognitive function and consciousness,which provides a new approach to study the mechanism of action of general an-esthetic drugs.Propofol is widely used in clinical practice,and its molecular mechanism has been deeply studied.The neural network mechanism of loss of consciousness induced by propofol is still unclear.This ar-ticle reviews the changes of electroencephalogram characteristics(including power spectrum,complexity,microstate,the functional connectivity,and brain network topology characteristics change)and corres-ponding brain functional changes of loss of conscionsness induced by propofol,the common general anesthet-ic,to provide a new idea for further research on the mechanism of action of anesthetic drugs and the depth of anesthesia monitoring.
