Long non-coding RNA and diseases
10.16352/j.issn.1001-6325.2024.10.1465
- VernacularTitle:长链非编码RNA与疾病
- Author:
Wenchao LI
1
;
Xiangsheng LI
;
Fuguang LI
;
Zhiyong ZHANG
;
Lei HUI
;
Wenke ZHOU
Author Information
1. 新乡医学院第一附属医院 神经外科,河南 新乡 453000
- Keywords:
non-coding RNA;
tumors;
nervous system;
disease;
epigenetics
- From:
Basic & Clinical Medicine
2024;44(10):1465-1469
- CountryChina
- Language:Chinese
-
Abstract:
Long non-coding RNA(lncRNA)is a class of endogenous non-coding RNA with a length of more than 200 nt.Due to lack of open reading frame(ORF),they lack the ability to directly encode proteins,but they play a crucial role in gene regulation.They are widely involved in epigenetics,transcription,translation,modification and degradation,thereby affecting the life activities of the body,and their expression imbalance is closely related to the occurrence and development of diseases.Therefore,analyzing the inherent characteristics of lncRNA and revealing its intrinsic role can not only deepen our understanding of human physiological and pathological processes,but also provide new ideas and potential solutions for the diagnosis,prevention and treatment of diseases.So as to provide references for the related research of lncRNAs.
