Establishment of Diagnostic Criteria for Spleen Deficiency with Dampness Accumulation Syndrome in Psoriasis Vulgaris by Literature Research and Delphi Method
10.13359/j.cnki.gzxbtcm.2024.11.034
- VernacularTitle:基于文献研究及德尔菲法构建寻常型银屑病脾虚湿蕴证的诊断标准
- Author:
Xiu-Li XIE
1
;
Ya LUO
;
Chuan-Jian LU
Author Information
1. 广州中医药大学第二附属医院/广东省中医院,广东 广州 510120;省部共建中医湿证国家重点实验室/广州中医药大学第二附属医院,广东 广州 510120;粤港澳中医药与免疫疾病研究联合实验室/广州中医药大学,广东 广州 510120;广东省中医药防治难治性慢病重点实验室/广州中医药大学第二附属医院,广东 广州 510120
- Keywords:
psoriasis vulgaris;
spleen deficiency with dampness accumulation syndrome;
literature research;
Delphi method;
diagnostic indicators
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
2024;41(11):3050-3057
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish the diagnostic criteria for psoriasis vulgaris of spleen deficiency with dampness accumulation syndrome by using the methods of literature research,subjective experts'experience evaluation and mathematical statistical analysis together.Methods An alternative item pool of symptoms and signs related to psoriasis vulgaris of spleen deficiency with dampness accumulation syndrome was constructed on the basis of the results of literature research.A four-round questionnaire survey was carried out among 32 experts nationwide using the Delphi method,and then the concentration and coordination of the experts'opinions on each of the alternative items were analyzed.In the third round of the survey,all of diagnostic indicators were classified into primary or secondary symptoms according to the weighting coefficients of each item,and then the judgment condition options for the diagnostic criteria of the symptoms were formed.Through the fourth-round of expert survey,the diagnostic mode and diagnostic conditions of spleen deficiency with dampness accumulation syndrome were clarified.Results The alternative diagnostic indicators were screened according to the concentration degree and the variation coefficient of experts'opinions,and 24 diagnostic indicators were obtained after merging the similar indicators,of which there were three primary symptoms(poor appetite and anorexia,loose stool,and pale and swollen tongue with tooth marks)and 21 secondary symptoms(abdominal distension,tastelessness in the mouth without thirst,obesity,drowsiness,fatigue and lack of strength,thready and smooth pulse,soft pulse,undigested food in the stool,and light-red skin lesions,etc.).The fourth-round expert survey confirmed that the necessary conditions for the diagnosis of psoriasis vulgaris of spleen deficiency with dampness accumulation syndrome were"the disease-location of the spleen","the disease-nature of qi deficiency"and"the disease-nature of dampness";the diagnostic criteria for psoriasis of spleen deficiency with dampness accumulation syndrome were as follows:(1)with three primary symptoms;(2)with two primary symptoms and any two of the secondary symptoms.Conclusion The diagnostic criteria for psoriasis vulgaris of spleen deficiency with dampness accumulation syndrome constructed in this study include both primary and secondary symptoms,with clarified conditions and being easy to be practiced clinically,and have good clinical credibility.
