Data Mining of Traditional Chinese Medicine Syndrome Differentiation and Treatment Patterns for Dengue Fever
10.13359/j.cnki.gzxbtcm.2024.09.039
- VernacularTitle:登革热中医证治规律的数据挖掘
- Author:
Ting WANG
1
;
Cheng-Xin LIU
;
Shao-Feng ZHAN
;
Yong JIANG
Author Information
1. 深圳市中西医结合医院,广东深圳 518104;广州中医药大学第一临床医学院,广东广州 510405;广州中医药大学第一附属医院,广东广州 510405;广州中医药大学岭南医学研究中心,广东广州 510405
- Keywords:
dengue fever;
syndrome of comorbidity of defense phase and qi phase;
syndrome of blazing of both qi phase and nutrient phase;
clearing heat;
removing toxin;
cooling blood;
Qingwen Baidu Decoction;
Paeoniae Radix Rubra;
Moutan Cortex;
Rehmanniae Radix;
data min
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
2024;41(9):2491-2499
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the patterns of traditional Chinese medicine(TCM)syndrome differentiation and treatment for dengue fever by using R language data visualization technology,so as to provide reference for TCM syndrome differentiation and treatment of dengue fever.Methods The related literature of dengue fever treated by Chinese medicine was retrieved from CNKI,Wanfang Data,and VIP.R-Studio software was used to conduct descriptive statistical analysis of the TCM syndromes,treatment methods,prescriptions and Chinese medicine in the literature of dengue fever treated by oral use of Chinese medicine.Based on Apriori algorithm,association rule mining and cluster analysis were carried out to explore the TCM syndrome and treatment patters of dengue fever.Results A total of 176 prescriptions for effective cases were extracted,and the included literature involved 29 syndromes,73 TCM treatment methods,56 classical prescriptions and 35 self-formulated prescriptions,and 179 Chinese medicinals.The syndrome of comorbidity of defense phase and qi phase and the syndrome of blazing of both qi phase and nutrient phase were the high-frequency syndromes of dengue fever treated by oral use of Chinese medicine.The high-frequency treatment methods covered heat-clearing therapy,toxin-removing therapy,blood-cooling therapy and dampness-resolving therapy.Qingwen Baidu Decoction was the most frequently-used prescription.Glycyrrhizae Radix et Rhizoma,Forsythiae Fructus,Scutellariae Radix,Gypsum Fibrosum,and Lonicerae Japonicae Flos were the frequently-used Chinese medinals.There were three drug combinations containing Paeoniae Radix Rubra,Moutan Cortex,and Rehmanniae Radix,and their correlation of association rules was the highest.Bubali Cornu,Moutan Cortex,Paeoniae Radix Rubra,Rehmanniae Radix,Lonicerae Japonicae Flos,Forsythiae Fructus,Gypsum Fibrosum,Scutellariae Radix,Anemarrhenae Rhizoma,and Glycyrrhizae Radix et Rhizoma were the core Chinese medicinals for the treatment of dengue fever.Conclusion The TCM syndromes of dengue fever are predominated by the syndrome of comorbidity of defense phase and qi phase and the syndrome of blazing of both qi phase and nutrient phase.The treatment of dengue fever with TCM is based on the principle of clearing heat toxin from the qi phase,cooling the nutrient-blood excess heat,resolving pathogenic dampness,and nourishing qi and yin.The treatment focuses on clearing qi phase and blood phase,and the application of removing stasis in febrile diseases should be stressed,thus to block the progression of the disease in time.
