Research progress on mechanism of early inflammation and ventricular remodeling after acute myocardial infarction
10.3760/cma.j.cn121382-20240116-00213
- VernacularTitle:早期炎症和心室重构在急性心肌梗死后作用机制的研究进展
- Author:
Weitong WANG
1
;
Linken LU
;
Jiajun LU
;
Jing CHEN
;
Hong SUN
Author Information
1. 华北理工大学基础医学院，河北省慢性疾病重点实验室，唐山 063000
- Keywords:
Acute myocardial infarction;
Early inflammation;
Ventricular remodeling
- From:
International Journal of Biomedical Engineering
2024;47(2):188-193
- CountryChina
- Language:Chinese
-
Abstract:
Acute myocardial infarction (AMI) is a prevalent and serious cardiovascular disease characterized by a complex inflammatory response and myocardial tissue remodeling. The early inflammatory response plays a key role in the aftermath of AMI, promoting myocardial injury and repair. At the same time, ventricular remodeling, as a physiological process after AMI, involves myocardial hypertrophy, fibrosis, dilation, and remodeling, which has a profound impact on cardiac function and prognosis. Therefore, it is of great significance to understand the mechanism of action of early inflammation and ventricular remodeling after AMI. In this paper, the mechanism of early inflammation and ventricular remodeling after AMI was systematically reviewed, focusing on the dynamic changes of inflammatory mediators after AMI and the correlation between ventricular remodeling and prognosis, hoping to provide guidance and reference for the prevention, treatment, and prognosis of AMI.
