Progress in the application of apolipoprotein B in cardiovascular disease risk prediction
10.3969/j.issn.1673-4130.2024.13.022
- VernacularTitle:载脂蛋白B在心血管疾病风险预测中的应用进展
- Author:
Hui HE
1
;
Qingqing LU
;
Xiaobing XIE
Author Information
1. 湖南中医药大学第一附属医院,湖南长沙 410007
- Keywords:
apolipoprotein B;
cardiovascular disease;
risk prediction;
application progress
- From:
International Journal of Laboratory Medicine
2024;45(13):1645-1650
- CountryChina
- Language:Chinese
-
Abstract:
Cardiovascular disease(CVD)is the leading cause of non communicable disease mortality in China,and its prevalence rate is increasing year by year,which has become the number one"killer"of human health.Studies have shown that apolipoprotein B(ApoB),as a risk factor for CVD,has certain advantages in assessing the progression of CVD.It can directly measure the number of low-density lipoprotein(LDL)parti-cles,and the test is not subject to fasting,so it can be used as the main measurement index for screening,diag-nosis and management of CVD.Therefore,this paper provides a review of the characteristics of ApoB,SWOT analysis of ApoB for CVD risk assessment,methods to reduce ApoB level and its role in CVD risk prediction,with a view to contributing to the clinical application of ApoB in CVD risk assessment,and better assisting in the early detection,prevention,and treatment of cardiovascular disease.