Progress on the influence of pregnant mothers with systemic lupus erythematosus on offsprings health and related prediction models
10.3760/cma.j.issn.1673-4408.2024.10.013
- VernacularTitle:系统性红斑狼疮合并妊娠母亲对子代健康的影响及相关预测模型的研究进展
- Author:
Yaqin ZHOU
1
;
Hua MEI
Author Information
1. 内蒙古医科大学附属医院新生儿科，呼和浩特 010000
- Keywords:
Systemic lupus erythematosus;
Pregnancy;
Offspring;
Prediction model
- From:
International Journal of Pediatrics
2024;51(10):710-715
- CountryChina
- Language:Chinese
-
Abstract:
Systemic lupus erythematosus（SLE）is an autoimmune disease characterized by an unclear etiology，the presence of multiple autoantibodies，and dysfunction in various systems and organs.The disease tends to recur and primarily affects women of childbearing age，potentially leading to adverse pregnancy outcomes（APO）.The main impacts of SLE on the health of offspring from pregnant mothers include fetal growth restriction，premature birth，small size for gestational age，neonatal lupus，as well as long-term health issues，such as neurocognitive disorders，mental or motor development disorders，allergic diseases，and cardiovascular diseases.By establishing a precise prediction model for APO in SLE combined pregnancies and implementing early interventions accordingly，it is possible to minimize APO occurrences and improve both short-term and long-term effects on offspring health.This article provides a comprehensive review about the effects of SLE on the health of offspring from pregnant mothers along with related prediction models.
