Progress on diagnosis and treatment of oral allergy syndrome
10.3760/cma.j.issn.1673-4408.2024.10.010
- VernacularTitle:口腔过敏综合征的诊治进展
- Author:
Tianyue LIU
1
;
Xueyan WANG
Author Information
1. 天津医科大学第二医院儿科300211
- Keywords:
Oral allergy syndrome;
Pollen-food allergy syndrome;
Food allergy;
Cross anaphylaxis
- From:
International Journal of Pediatrics
2024;51(10):694-698
- CountryChina
- Language:Chinese
-
Abstract:
Oral allergy syndrome（OAS），also known as pollen-food allergy syndrome，is a type of food allergy caused by the cross-reaction of inhaled allergens with food allergens.The clinical manifestations are oral symptoms such as itching，pain and numbness after ingestion of food allergens，and systemic symptoms may be accompanied in severe cases.The main cross-reactive antigens are PR-10 family，lipid transfer proteins，prefibrins and storage proteins.The diagnosis of OAS is mainly based on clinical history，oral food challenge，skin prick test，antigen specific IgE detection，allergen component diagnosis，basophil activation test，etc.OAS patients should strictly avoid allergic foods，and use antihistamines and epinephrine when necessary.Biologics，specific immunotherapy，and oral tolerance induction can also be used to treat OAS，but the efficacy is still controversial.
