Progress on blood biomarkers for inflammatory bowel disease in children
10.3760/cma.j.issn.1673-4408.2024.09.004
- VernacularTitle:儿童炎症性肠病血液生物标志物研究进展
- Author:
Xi HE
1
;
Xuemei ZHONG
Author Information
1. 首都儿科研究所附属儿童医院消化内科，北京 100020
- Keywords:
Inflammatory bowel disease;
Biomarkers;
Diagnostic methods
- From:
International Journal of Pediatrics
2024;51(9):590-594
- CountryChina
- Language:Chinese
-
Abstract:
Inflammatory bowel disease is a common and refractory chronic disease in digestive system diseases，and its prevalence is increasing year by year.Delayed diagnosis is prevalent in patients with inflammatory bowel disease，affecting the course and outcome of the patient's illness.Early identification and early diagnosis can significantly improve the prognosis of patients with inflammatory bowel disease.Because of the traumatic nature of endoscopic testing，it is important to find reliable non-invasive test markers.This paper aims to introduce the recent progress of blood biomarkers with early diagnostic value in pediatrics，and summarize several novel markers for distinguishing inflammatory bowel disease from non-inflammatory bowel disease，ulcerative colitis and Crohn's disease，as well as discussing the differences of inflammatory bowel disease between children and adults，and providing suggestions for future research to help clinicians identify inflammatory bowel disease accurately as soon as possible and improve patient prognosis.
