Progress on correlation between Guillain-Barré syndrome spectrum diseases and anti-glycolipid antibodies in children
10.3760/cma.j.issn.1673-4408.2024.06.009
- VernacularTitle:儿童吉兰-巴雷综合征谱系疾病与抗糖脂抗体相关性研究进展
- Author:
Xinlu MIAO
1
;
Junmei ZHANG
Author Information
1. 中国医科大学附属盛京医院小儿神经内科，沈阳 110004
- Keywords:
Children;
Guillain-Barré syndrome spectrum disorder;
Anti-glycolipid antibodies;
Clinical manifestations;
Prognosis
- From:
International Journal of Pediatrics
2024;51(6):398-401
- CountryChina
- Language:Chinese
-
Abstract:
Guillain-Barré syndrome（GBS）is a class of immune-mediated acute inflammatory peripheral neuropathy.With the in-depth understanding of its phenotype，a spectrum disease including classic GBS and variant GBS has been gradually formed.A number of studies at home and abroad have found that anti-peripheral nerve membrane surface glucolipid antibodies，including anti-ganglioside antibodies and anti-Sulfatide antibodies，are closely related to GBS spectrum diseases.As a part of peripheral nerve antibodies，anti-glycolipid antibodies play an important role in the diagnosis，clinical classification，disease assessment and prognostic assessment of GBS spectrum diseases.The article reviews the progress on the correlation between anti-glycolipid antibody and GBS spectrum disease in children，in order to provide clinical reference.
