Progress on peripheral blood biomarkers in children with bronchial asthma
10.3760/cma.j.issn.1673-4408.2024.06.003
- VernacularTitle:儿童支气管哮喘外周血生物标志物的研究进展
- Author:
Yuping SONG
1
;
Rong LUO
Author Information
1. 重庆医科大学附属儿童医院呼吸科 儿童发育疾病研究教育部重点实验室 国家儿童健康与疾病临床医学研究中心 儿童发育重大疾病国家国际科技合作基地 儿科学重庆市重点实验室 400014
- Keywords:
Children;
Bronchial asthma;
Peripheral blood;
Biomarker
- From:
International Journal of Pediatrics
2024;51(6):369-372
- CountryChina
- Language:Chinese
-
Abstract:
Bronchial asthma is one of the common chronic respiratory diseases in children，mainly manifested as airway hyperresponsiveness and chronic airway inflammation.The disease varies in phenotype，clinical presentation，course and response to treatment.Therefore，more precise and accessible biomarkers are needed for diagnosis and evaluation.Clinical assay of peripheral blood biomarkers only requires blood samples to be collected，can be repeatedly extracted and easily quantified，and are expected to improve the efficiency of asthma diagnosis and treatment，becoming a choice for clinical diagnosis and treatment.This article reviews the research progress of peripheral blood biomarkers in identifying the phenotype of childhood asthma，evaluating the severity，and predicting the therapeutic effect in recent years，with the aim to provide personalized medical strategies for children with asthma.
