Progress on short-chain fatty acids and gastrointestinal function in children
10.3760/cma.j.issn.1673-4408.2024.05.004
- VernacularTitle:短链脂肪酸与儿童胃肠道功能的研究进展
- Author:
Qingqing HE
1
;
Yongkun HUANG
Author Information
1. 昆明医科大学第一附属医院儿科 650032
- Keywords:
Short-chain fatty acids;
Defecation frequency;
Intestinal flora;
Metabolites
- From:
International Journal of Pediatrics
2024;51(5):302-306
- CountryChina
- Language:Chinese
-
Abstract:
Short-chain fatty acids are metabolites produced by anaerobic bacteria fermenting undigested carbohydrates in the cecum and colon.After being absorbed in the colon，they can regulate intestinal energy metabolism，maintain intestinal mucosal barrier function，regulate intestinal immune function，affect intestinal secretion and absorption，and regulate intestinal microecology through the above functions，thereby changing the frequency of defecation in children.With the in-depth understanding of intestinal microecology，it has been found that the metabolites of intestinal flora also play an important role in the human body.When the frequency of defecation in children changes，the composition of intestinal flora changes，and the content of short-chain fatty acids produced by intestinal flora metabolism also changes.This article reviews the role and mechanism of short-chain fatty acids in children's different defecation frequencies，and provides treatment ideas for children's different defecation frequencies.
