Application and progress of ultrasound-stimulated microbubble cavitation in novel adjuvant therapies
10.16781/j.CN31-2187/R.20230703
- VernacularTitle:超声激励微泡空化在新型辅助治疗中的应用及进展
- Author:
Yijia LIU
1
;
Xiaoyi TANG
;
Jiaqi ZHAO
Author Information
1. 海军军医大学(第二军医大学)第二附属医院超声诊断科,上海 200003;同济大学附属上海市第四人民医院超声医学科,上海 200434
- Keywords:
ultrasonic therapy;
ultrasound contrast agent;
nanotechnology;
cavitation therapy;
musculoskeletal ultrasound
- From:
Academic Journal of Naval Medical University
2024;45(11):1419-1424
- CountryChina
- Language:Chinese
-
Abstract:
Ultrasound-stimulated microbubble cavitation(USMC)is a cavitation phenomenon triggered by oscillating microbubbles in ultrasound field,and this effect has led to breakthroughs in improving the permeability of cell membranes,enhancing the sensitivity of tumor cells to chemotherapy or immunotherapy,and increasing the penetration of thrombolytic drugs into blood clots and vascular recanalization.In recent years,the cross-fertilization of ultrasound medicine and materials science have given rise to the study of ultrasound-responsive multifunctional nanobubble to enhance USMC treatment.This article reviews the application and research progress of USMC in improving tissue perfusion in ischemic diseases,tumor chemotherapy and immunotherapy,ultrasonic thrombolysis,and other treatments.
