Correlation analysis of phase angle with nutritional risk and clinical outcomes in patients with severe acute pancreatitis
10.16151/j.1007-810x.2024.04.008
- VernacularTitle:重症急性胰腺炎并发ARDS病人相位角与营养状态及临床结局的相关性研究
- Author:
Lan DING
1
;
Yue FU
;
Ze-Hua ZHAO
;
Hong-Lin YAO
;
Xiang-Hong YE
Author Information
1. 中国人民解放军东部战区总医院全军普通外科研究所,江苏南京 210002
- Keywords:
Severe acute pancreatitis;
Phase angle;
Nutritional status;
Clinical outcome
- From:
Parenteral & Enteral Nutrition
2024;31(4):252-256
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the relationship between phase angle (PA) and nutritional status,duration of mechanical ventilation,length of intensive care unit (ICU) stay,and clinical outcomes in patients with severe acute pancreatitis (SAP) complicated with ARDS. Methods:The clinical data of patients with SAP complicated with ARDS admitted to the surgical ICU,Jinling hospital,medical school of Nanjing University,from July 2023 to March 2024 were retrospectively collected. Patients are divided into low-PA group and normal-PA group based on phase angle. The correlation analysis between phase angle,nutritional status,and clinical outcomes,and evaluation of risk factors for mortality in patients with SAP combined with ARDS were performed. Result:A total of 83 patients with SAP complicated with ARDS were included in this study. PA was negatively correlated with nutritional risk scores (rs=-0.352,P=0.001),duration of mechanical ventilation (rp=-0.475,P<0.001),length of ICU stay (rp=-0.313,P=0.004),and mortality (rs=-0.371,P=0.001). Univariate analysis showed statistically significant differences in age,PA value,and duration of mechanical ventilation for predicting mortality (P<0.05);Multivariate analysis showed that the PA value was an independent risk factor for mortality (P<0.05). Conclusion:PA is significantly correlated with clinical outcomes,such as nutritional risk,duration of mechanical ventilation,length of ICU stay and mortality,and may be a promising biomarker in future.
