Preliminary application of drug-coated balloon in patients with symptomatic intracranial vertebrobasilar artery stenosis
10.3760/cma.j.cn112139-20200514-00381
- VernacularTitle:药物涂层球囊在症状性颅内椎基底动脉狭窄中的初步应用
- Author:
Ximeng YANG
1
;
Jun LU
;
Peng QI
;
Junjie WANG
;
Shen HU
;
Kunpeng CHEN
;
Daming WANG
Author Information
1. 北京医院神经外科 国家老年医学中心 中国医学科学院老年医学研究院 100730
- Keywords:
Angioplasty, balloon;
Intracranial arteriosclerosis
- From:
Chinese Journal of Surgery
2020;58(12):904-908
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the safety and short-term efficacy of drug-coated balloon (DCB) angioplasty for patients with symptomatic intracranial vertebrobasilar artery stenosis.Methods:Sixteen patients with symptomatic intracranial vertebrobasilar artery stenosis who received DCB angioplasty from September 2018 to December 2019 at Department of Neurosurgery, Beijing Hospital were retrospectively reviewed. There were 15 males and 1 female, aged (63.1±9.2) years (range: 48 to 77 years). Patients′ demographics, lesions characteristics, complications, clinical and imaging follow-up data were collected and analyzed.Results:A total of 19 symptomatic intracranial vertebrobasilar artery stenosis were successfully treated with DCB.The degree of stenosis of lesion was 75% (20%) ( M( Q R)) before operation and 0 (20%) after operation. One posterior circulation stroke due to perforator artery occlusion happened in peri-procedural period.With a mean imaging follow-up time of 5.5 months, there was no restenosis occurred. Within a mean clinical follow-up period of 6.3 months, no new symptoms happened. Conclusion:For patients with symptomatic intracranial vertebrobasilar artery stenosis, DCB angioplasty seems relatively high safety with satisfactory short-term clinical and imaging outcomes.
