Research and application progress of percutaneous aponeurotomy and lipofilling in scar repair
10.3760/cma.j.cn114453-20210926-00393
- VernacularTitle:经皮针刺筋膜切开自体脂肪移植术修复瘢痕的研究及应用进展
- Author:
Lu CUI
1
;
Qinghua YANG
Author Information
1. 中国医学科学院北京协和医学院整形外科医院外耳整形再造一中心，北京 100144
- Keywords:
Adipose tissue;
Percutaneous aponeurotomy and lipofilling;
Adipose-derived stem cells;
Scar
- From:
Chinese Journal of Plastic Surgery
2023;39(8):916-920
- CountryChina
- Language:Chinese
-
Abstract:
Adipose-derived stem cells(ADSCs)are considered to play important roles in wound repair, tissue remodeling and suppression of pathological fibrogenesis after injury and thus have shown a great potential in the improvement of contracture, adhesion and dysfunction caused by scar tissue. The application of autologous fat can decrease scar size and provides better color quality and scar pliability, thus has been an important treatment of scar caused by trauma, radiotherapy, and surgery. Based on that, the percutaneous aponeurotomy and lipofilling (PALF) loosens restrictive fibers by puncturing cicatrix and endogenous aponeurosis directly, making a transformation of a restrictive cicatrix into a regenerative matrix that expands a tight scar or constriction into a loose, three-dimensional recipient scaffold that is receptive to fat grafts. It improves the texture, color, elasticity, and many other properties of mature scar in a safe and simple way and represents a regenerative alternative to reconstructive flap surgery. This study reviews the progress of research and application regarding PALF in scar correction to provide new insight into the therapeutic potential of ADSCs.
