Application of ultrasensitive single molecule immunoassay technology in clinical biomarker detection
10.3760/cma.j.cn112150-20231212-00431
- VernacularTitle:超敏单分子免疫检测技术在临床生物标志物检测中的应用
- Author:
Wencan JIANG
1
;
Guojun ZHANG
Author Information
1. 首都医科大学附属北京天坛医院实验诊断中心，国家药品监督管理局体外诊断试剂质量控制重点实验室，北京市免疫试剂临床工程技术研究中心，北京 100070
- Keywords:
Single molecule immunoassay;
Ultrasensitive detection;
Neuroscience;
Biomarkers;
Clinical applications
- From:
Chinese Journal of Preventive Medicine
2024;58(8):1154-1160
- CountryChina
- Language:Chinese
-
Abstract:
Single-molecule immunoassay technology represents an ultrasensitive immunoassay method that enables the resolution and detection of individual biomolecules at the nanoscale. This article highlights various representative techniques and clinical applications of single-molecule immunoassay technology, while also discussing the current challenges and future development directions. Through multiple optimizations at both the technical and commercial levels, single-molecule immunoassay technology exhibits unique advantages in real-time detection, disease diagnosis and treatment, and medical research. This technology is poised to contribute to the advancement of precision medicine by integrating individualized detection methods into clinical practice.
